Nature Neuroscience 9, 487 - 488 (2006)
Published online: 26 March 2006; | doi:10.1038/nn1676
Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemiaAnnett Spudich, Ertugrul Kilic, Hongyi Xing, Ülkan Kilic, Katharina M Rentsch, Heidi Wunderli-Allenspach, Claudio L Bassetti
& Dirk M Hermann Supplementary Fig. 1 (pdf 176K)
Mdr-1 expression is increased in the ischemic brain. Supplementary Fig. 2 (pdf 32K)
The Mdr-1 inhibitor TQD preferably increases brain concentrations of FK506 and rifampicin in the ischemic brain. Supplementary Fig. 3 (pdf 28K)
Regimen of TQD, FK506 and rifampicin (Rif) delivery used in order to study the role of the Mdr-1 transporter in post-ischemic neuroprotection. Supplementary Methods (pdf 104K)
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