Another BOLD role for astrocytes: coupling blood flow to neural activity
David J Rossi
David J. Rossi is at the Neurological Sciences Institute, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon 97006, USA. rossid@ohsu.edu
Increased local blood flow in response to neural activity is critical for brain function and the basis for functional imaging. Takano et al. now show that in vivo, astrocytes are central in translating neural activity into vasodilation via a mechanism involving COX1 metabolites.
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