Indirect-pathway neurons lose their spines in Parkinson disease
Charles R Gerfen
The author is at the Laboratory of Systems Neuroscience, National Institute of Mental Health, 35 Convent Drive, 3A-1000, Bethesda, Maryland 20892, USA.
gerfenc@mail.nih.gov
The Cav1.3 calcium channel is found on striatopallidal neurons expressing the D2 dopamine receptor. A new study finds that in an animal model of Parkinson disease, this channel is involved in degeneration of dendritic spines on striatal projection neurons.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
