Nature Neuroscience
- 9, 1469 - 1471 (2006)
Published online: 19 November 2006; | doi:10.1038/nn1809
fruitless regulates aggression and dominance in DrosophilaEleftheria Vrontou1, Steven P Nilsen2, Ebru Demir1, Edward A Kravitz2 & Barry J Dickson11
Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030 Vienna, Austria. 2
Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, Massachusetts 02115, USA.
Correspondence should be addressed to Barry J Dickson dickson@imp.ac.at When competing for resources, two Drosophila melanogaster flies of the same sex fight each other. Males and females fight with distinctly different styles, and males but not females establish dominance relationships. Here we show that sex-specific splicing of the fruitless gene plays a critical role in determining who and how a fly fights, and whether a dominance relationship forms.
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