Nature Neuroscience
- 9, 1461 - 1463 (2006)
doi:10.1038/nn1206-1461
High times for memory: cannabis disrupts temporal coordination among hippocampal neuronsIvan Soltesz1 & Kevin Staley21
Ivan Soltesz is at the Department of Anatomy & Neurobiology, University of California, Irvine, California 92697, USA. 2
Kevin Staley is at the Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. kstaley@partners.org
Exogenous cannabinoid receptor agonists impair hippocampus-dependent learning and decrease the power of hippocampal electroencephalographic activity. A new paper shows that cannabinoids desynchronize neuronal assemblies without affecting average firing rates, and that this effect correlates with memory deficits in individuals.
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