Nature Neuroscience
- 9, 1237 - 1239 (2006)
Published online: 24 September 2006; | doi:10.1038/nn1778
NMDA receptors are critical for unleashing consolidated auditory fear memoriesCyrinne Ben Mamou, Karine Gamache & Karim Nader
Psychology Department, McGill University, 1205 Dr. Penfield Avenue, Montreal, Quebec H3A 1B1, Canada.
Correspondence should be addressed to Karim Nader karim.nader@mcgill.ca Memories are dynamic and can change when recalled. The process that returns memories to a labile state during remembering is unclear. We found that the presence of NMDA, but not AMPA, receptor antagonists in the amygdala prior to recall prevented the consolidated fear memory from returning to a labile state. These findings suggest that NMDA receptors in the amygdala are critical for transforming a memory from a fixed to a labile state.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|
