Barry J. Dickson is at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3-5, A-1030 Vienna, Austria. dickson@imp.univie.ac.at
Certain Wnts attract ascending somatosensory axons up the spinal cord toward the brain. A study in this issue shows that other Wnts guide corticospinal axons down the spinal cord, not by an attractive mechanism but by repulsion through the receptor Ryk.
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