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Blue genes: wiring the brain for depression

Nature Neuroscience volume 8, pages 701–703 (2005)Cite this article

How do genes act in the brain to influence susceptibility to mental illness? An imaging study suggests that healthy carriers of a gene variant associated with depression risk have decreased brain volume and neural coupling in affective circuitry involved in depression.

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Figure 1: Differences in processing of emotional stimuli between s allele carriers (blue arrows) and homozygous l allele carriers (yellow arrows).

Debbie Maizels

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  1. Department of Psychology, Emory University, 532 North Kilgo Circle, Atlanta, 30322, Georgia, USA

    Stephan Hamann

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  1. Stephan Hamann
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Hamann, S. Blue genes: wiring the brain for depression. Nat Neurosci 8, 701–703 (2005). https://doi.org/10.1038/nn0605-701

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