Jane Sullivan is at the Department of Physiology and Biophysics, University of Washington School of Medicine, Box 357290, Seattle, Washington 98195, USA. jmsull@u.washington.edu
Activation of G protein−coupled receptors can inhibit secretion of neurotransmittters and hormones. Two recent reports in Nature Neuroscience show that this inhibition is due to G binding to SNAP-25, directly blocking the vesicle fusion machinery.
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binding to SNAP-25, directly blocking the vesicle fusion machinery.
