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Illuminating the calcium sensor for exocytosis in a flash

Nature Neuroscience volume 8, pages 402–404 (2005)Cite this article

A new paper quantifies the dependence of synaptic transmission on transient local changes in internal calcium, examining the equilibrium dynamics of the calcium sensor for exocytosis and its contribution to short-term changes in synaptic strength.

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Figure 1: Paired recordings and laser photolysis of caged calcium in the calyx of Held synapse.

References

  1. Heidelberger, R. Rev. Physiol. Biochem. Pharmacol. 143, 1–80 (2001).

    Article  CAS  Google Scholar 

  2. Bollmann, J.H. & Sakmann, B. Nat. Neurosci. 8, 426–434 (2005).

    Article  CAS  Google Scholar 

  3. Sätzler, K. et al. J. Neurosci. 22, 10567–10579 (2002).

    Article  Google Scholar 

  4. Sakaba, T. & Neher, E. J. Neurosci. 21, 462–476 (2001).

    Article  CAS  Google Scholar 

  5. Bollmann, J.H., Sakmann, B. & Borst, J.G. Science 289, 953–957 (2000).

    Article  CAS  Google Scholar 

  6. Schneggenburger, R. & Neher, E. Nature 406, 889–893 (2000).

    Article  CAS  Google Scholar 

  7. Felmy, F., Neher, E. & Schneggenburger, R. Neuron 37, 801–811 (2003).

    Article  CAS  Google Scholar 

  8. Taschenberger, H. & von Gersdorff, H. J. Neurosci. 20, 9162–9173 (2000).

    Article  CAS  Google Scholar 

  9. Chuhma, N., Koyano, K. & Ohmori, H. J. Physiol. (Lond.) 530, 93–104 (2001).

    Article  CAS  Google Scholar 

  10. Wimmer, V.C., Nevian, T. & Kuner, T. Pflugers Arch. 449, 319–333 (2004).

    CAS  PubMed  Google Scholar 

  11. Iwasaki, S. & Takahashi, T. J. Physiol. (Lond.) 509, 419–423 (1998).

    Article  CAS  Google Scholar 

  12. Felmy, F. & Schneggenburger, R. Eur. J. Neurosci. 20, 1473–1482 (2004).

    Article  Google Scholar 

  13. Taschenberger, H., Leão, R.M., Rowland, K.C., Spirou, G.A. & von Gersdorff, H. Neuron 36, 1127–1143 (2002).

    Article  CAS  Google Scholar 

  14. Augustine, G.J. Curr. Opin. Neurobiol. 11, 320–326 (2001).

    Article  CAS  Google Scholar 

  15. Borst, J.G. & Sakmann, B. Nature 383, 431–434 (1996).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Neurobiology and Anatomy at the University of Texas Medical School at Houston, Houston, 77030, Texas, USA

    Ruth Heidelberger

  2. The Vollum Institute, Oregon Health and Science University, Portland, 97239, Oregon, USA

    Henrique von Gersdorff

Authors
  1. Ruth Heidelberger
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  2. Henrique von Gersdorff
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Heidelberger, R., von Gersdorff, H. Illuminating the calcium sensor for exocytosis in a flash. Nat Neurosci 8, 402–404 (2005). https://doi.org/10.1038/nn0405-402

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