Scott A. Small is at the Taub Institute for Research on Alzheimer Disease and the Aging Brain, the Department of Neurology, and the Center for Neurobiology of Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA. sas68@columbia.edu
A new study shows that amyloid plaques tagged with fluorinated ligand can be detected with 19F MRI in transgenic mice. The superior signal to noise of this technique is a major step toward visualizing the histopathology of Alzheimer disease in living patients.
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