Controlling stress: how the brain protects itself from depression
Trevor W Robbins
Trevor W Robbins is in the Department of Experimental Psychology and the MRC Centre for Behavioural and Clinical Neuroscience at the University of Cambridge, Cambridge, UK. twr2@cam.ac.uk
Having control over a stressful situation can reduce its negative physiological and cognitive consequences. In this issue, a new study in rats suggests that descending inputs from the prefrontal cortex to the serotonergic midbrain signal the controllability of stress.
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