Stem cells in the injured spinal cord: reducing the pain and increasing the gain
Sandra Klein
& Clive N Svendsen
Sandra Klein and Clive N. Svendsen are at the Waisman Center at the University of Wisconsin, Madison, Wisconsin 53705, USA. svendsen@waisman.wisc.edu
Stem cells transplanted after spinal cord injury mostly generate astrocytes, which can promote aberrant sprouting of sensory neurons, leading to allodynia. Making cells produce more oligodendrocytes reduces allodynia and improves functional recovery.
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