Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice

Marta Paterlini^1, 2, Stanislav S Zakharenko^3, 9, Wen-Sung Lai^1, 2, Jie Qin⁴, Hui Zhang⁵, Jun Mukai¹, Koen G C Westphal⁶, Berend Olivier⁶, David Sulzer⁵, Paul Pavlidis⁴, Steven A Siegelbaum^3, 7, 8, Maria Karayiorgou² & Joseph A Gogos^1, 3

¹  Department of Physiology and Cellular Biophysics, Columbia University College of Physicians and Surgeons, 701 West 168th Street, New York, New York 10032, USA.

²  Human Neurogenetics Laboratory, Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

³  Center for Neurobiology and Behavior, Columbia University, 722 West 168th Street, New York, New York 10032, USA.

⁴  Genome Center and Department of Biomedical Informatics, Columbia University College of Physicians and Surgeons, 1150 St. Nicholas Avenue, New York, New York 10032, USA.

⁵  Departments of Neurology and Psychiatry, Columbia University College of Physicians and Surgeons, 701 West 168th Street, New York, New York 10032, USA.

⁶  Department of Pharmacology, University of Utrecht, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands.

⁷  Howard Hughes Medical Institute, Columbia University, 722 West 168th Street, New York, New York 10032, USA.

⁸  Department of Pharmacology, Columbia University, 722 West 168th Street, New York, New York 10032, USA.

⁹  Present address: Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, Tennessee 38105, USA.

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