Nature Neuroscience 8, 1491 - 1493 (2005)
Published online: 2 October 2005; | doi:10.1038/nn1544
The cerebellum communicates with the basal gangliaEiji Hoshi1, 2, 3, Léon Tremblay4, Jean Féger4, Peter L Carras1, 2
& Peter L Strick1, 2, 51
Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA. 2
Center for the Neural Basis of Cognition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA. 3
Tamagawa University Research Institute, Machida, Tokyo 194-8610 Japan. 4
Neurologie et Thérapeutique expérimentale (INSERM U679), Hôpital de la Salpêtrière, 47 boulevard de l'Hôpital, 75651 Paris CEDEX 13, France. 5
Pittsburgh Veterans Affairs Medical Center, Pittsburgh, Pennsylvania 15261, USA.
Correspondence should be addressed to Peter L Strick strickp@pitt.edu The cerebral cortex is interconnected with two major subcortical structures: the basal ganglia and the cerebellum. How and where cerebellar circuits interact with basal ganglia circuits has been a longstanding question. Using transneuronal transport of rabies virus in macaques, we found that a disynaptic pathway links an output stage of cerebellar processing, the dentate nucleus, with an input stage of basal ganglia processing, the striatum.
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