Klaus-Armin Nave and Markus Schwab are at the Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Hermann-Rein-Str. 3, 37075 Göttingen, Germany. nave@em.mpg.de
Not all axons in a peripheral nerve are myelinated. A recent study shows that the expression of neuregulin-1 on an axon membrane determines whether immature Schwann cells will differentiate into myelinating Schwann cells.
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