Shape-shifting at a cerebellar synapse allows submillisecond signaling
Dwight E Bergles
Dwight E. Bergles is at the Department of Neurobiology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA. dbergles@jhmi.edu
Synaptic currents become faster with age. A new study uses electron microscopy, physiology and modeling to show that the progressive speeding of AMPA receptor−mediated synaptic currents during development results from changes in the structure of the synapse rather than the composition of postsynaptic receptors.
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