In a technical tour de force, whole-cell patch clamp in tiny C. elegans touch receptor neurons in vivo is used to directly record currents in response to mechanical force, providing the first direct evidence that specific proteins are mechanotransducers.
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Ronan, D., Gillespie, P. Metazoan mechanotransduction mystery finally solved. Nat Neurosci 8, 7–8 (2005). https://doi.org/10.1038/nn0105-7
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DOI: https://doi.org/10.1038/nn0105-7
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