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Brief Communication
Nature Neuroscience  8, 24 - 25 (2004)
Published online: 12 December 2004; | doi:10.1038/nn1364

Discriminating emotional faces without primary visual cortices involves the right amygdala

Alan J Pegna1, 2, Asaid Khateb2, Francois Lazeyras3 & Mohamed L Seghier3, 4

1  Centre for Cognitive Neuroscience, School of Psychology, University of Wales Bangor, Penrallt Road, Gwynedd LL57 2AS, UK.

2  Neuropsychology Unit, Neurology Clinic, Department of Clinical Neuroscience and Dermatology, Geneva University Hospital, Rue Micheli-du-Crest 24, CH-1211 Geneva 14, Switzerland.

3  Department of Radiology, Geneva University Hospital, Rue Micheli-du-Crest 24, CH-1211 Geneva 14, Switzerland.

4  Laboratory of Neurology and Neuroimaging of Cognition, Department of Fundamental Neuroscience, University Medical Center, Rue Michel-Servet 1, CH-1211 Geneva 4, Switzerland.

Correspondence should be addressed to Alan J Pegna alan.pegna@hcuge.ch
Destruction of the brain's primary visual areas leads to blindness of cortical origin. Here we report on a subject who, after bilateral destruction of his visual cortices and ensuing cortical blindness, could nevertheless correctly guess the type of emotional facial expression being displayed, but could not guess other types of emotional or non-emotional stimuli. Functional magnetic resonance imaging showed activation of the right amygdala during the unconscious processing of emotionally expressive faces.


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Nature Neuroscience
ISSN: 1097-6256
EISSN: 1546-1726
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