 | About the cover
August 2004 - Vol 7 No 8
Nature Neuroscience 7 (2004)
| | |  | Neurons in primary visual cortex demonstrate orientation selectivity-preferentially responding to bars or gratings tilted at certain angles-but the anatomical basis for this selectivity is unclear. Mooser and colleagues examined the spatial arrangement of feedforward axonal connections from
non-oriented neurons in layer 4 to neurons in layer 2/3, where orientation selectivity first arises in tree shrew visual cortex. They found that terminations in layer 2/3 were distributed most densely along the axis of preferred orientation of the target neurons. These results provide anatomical evidence of an intracortical feedforward mechanism for orientation selectivity (pp 796 and 872)
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