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News and Views
Nature Neuroscience  7, 793 - 794 (2004)
doi:10.1038/nn0804-793

Controlling neuron number: does Numb do the math?

David R Castañeda-Castellanos1 & Arnold R Kriegstein2

1  David R. Castañada-Castellanos is in the Departments of Neurology and Physiology and Cellular Biophysics, Columbia University, New York, New York, USA.

2  Arnold R. Kriegstein is in the Departments of Neurology and Pathology and the center for Neurobiology and Behavior, Columbia University, New York, New York, USA. ark17@columbia.edu

Numb is an important developmental protein that functions in fate determination, differentiation and cell maturation, but its role in mammalian neural progenitors has been controversial. A new paper uses a clever approach to attempt to reconcile the opposing views.

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Nature Neuroscience
ISSN: 1097-6256
EISSN: 1546-1726
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