1
Nelson Spruston is in the Department of Neurobiology and Physiology and a member of the Institute for Neuroscience, Northwestern University, Evanston, Illinois 60208, USA.
2
William L. Kath is in the Department of Engineering Sciences and Applied Mathematics and a member of the Institute for Neuroscience, Northwestern University, Evanston, Illinois 60208, USA.
Pyramidal neurons integrate synaptic inputs arriving on a structurally and functionally complex dendritic tree that has nonlinear responses. A study in this issue shows that nonlinear computation occurs in individual dendritic branches, and suggests a possible approach to building neural network models directly connected to the behavior of real neurons and synapses.
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