Brief Communication abstract


Nature Neuroscience 7, 497 - 498 (2004)
Published online: 18 April 2004 | doi:10.1038/nn1238

Dorsal anterior cingulate cortex shows fMRI response to internal and external error signals

Clay B Holroyd1,6, Sander Nieuwenhuis1,2,6, Nick Yeung1, Leigh Nystrom1,3, Rogier B Mars4,5, Michael G H Coles4 & Jonathan D Cohen1,3

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In our event-related functional magnetic resonance imaging (fMRI) experiment, participants learned to select between two response options by trial-and-error, using feedback stimuli that indicated monetary gains and losses. The results of the experiment indicate that error responses and error feedback activate the same region of dorsal anterior cingulate cortex, suggesting that this region is sensitive to both internal and external sources of error information.

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  1. Department of Psychology, Green Hall, Princeton University, Princeton, New Jersey 08544, USA.
  2. Department of Cognitive Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands.
  3. Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, New Jersey 08544, USA.
  4. F. C. Donders Centre for Cognitive Neuroimaging, Adelbertusplein 1, 6525 EK Nijmegen, The Netherlands.
  5. Nijmegen Institute for Cognition and Information, University of Nijmegen, Box 9104, 6500 HE, Nijmegen, The Netherlands.
  6. These authors contributed equally to this work.

Correspondence to: Clay B Holroyd1,6 e-mail: cholroyd@princeton.edu



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