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Volume 7 Issue 4, April 2004

In competitive games, the outcome of one player's choices often depends on the strategy chosen by each opponent. Lee and colleagues now show that activity in the prefrontal cortex may provide signals to update estimates of expected reward in monkeys playing a simple game against a computer opponent. Such signals could underlie the generation of random behavior for strategic purposes. The authors also used a reinforcement-learning algorithm to predict the monkeys' choices. (pp 319 and 404).

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