Nature Neuroscience
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November 2004 - Vol 7 No 11
Nature Neuroscience 7 (2004)
 
Cover image detail
During development, neurons migrate along glial fibers to take their place within the cortical layers. Hatten and colleagues show that overexpression of mPar6alpha disrupts the coordinated cytoskeletal mechanisms that enable this migration. The cover image shows young cerebellar granule cells migrating along Bergmann glia fibers. The centrosome and nuclei are labeled with dynein intermediate chain (red), and the perinuclear microtubule cage is marked with beta-tubulin (green). In the migrating neurons, the centrosome is positioned forward of the nucleus. Image rendered by Nick Didkovsky. pp 1169 and 1195
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