Steven J Burden1, Christian Fuhrer3
& Stevan R Hubbard2
1
S.J.B. is in the Molecular Neurobiology Program, New York University School of Medicine, New York, New York 10016, USA.
2
S.R.H. is in the Structural Biology Program at the Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA.
3
C.F. is at the Brain Research Institute, University of Zürich-Irchel, CH-8057 Zürich, Switzerland.
During neuromuscular synapse development, clustering of acetylcholine receptors requires Agrin/MuSK signaling. The non-receptor tyrosine kinases Abl1 and Abl2 are now suggested to be the signals downstream of MuSK leading to receptor clustering.
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