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Nature Neuroscience  6, 437 - 438 (2003)
doi:10.1038/nn0503-437

L-DOPA, dyskinesia and striatal plasticity

Stephen Dunnett

The author is at the School of Biosciences, Cardiff University, Cardiff, Wales CF10 3US, UK. dunnettsb@cf.ac.uk

Long-term use of L-DOPA as a treatment for Parkinson disease can induce uncontrollable movements. A new report attributes this side effect to abnormal downregulation of synaptic plasticity.

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Nature Neuroscience
ISSN: 1097-6256
EISSN: 1546-1726
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