Nature Neuroscience6, 1162 - 1168 (2003)
Published online: 28 September 2003; | doi:10.1038/nn1131
Vertebrate neurogenesis is counteracted by Sox1−3 activity
Magdalena Bylund, Elisabeth Andersson, Bennett G Novitch
& Jonas Muhr
Supplementary Fig. 1. (jpg 55K)
Regulation of c-Hairy1 and c-Hes5 expression by Ngn2 and Sox3. (a-c) Misexpression of Ngn2 (a) increased the expression of c-Hairy1 (b) in a fraction of the transfected cell, whereas c-Hes5 expression was markedly upregulated throughout the Ngn2 electroporated side (c). Embryos were analyzed 10 h after electroporation. (d-f) The expression of c-Hairy1 was similar in the Sox3 electroporated side compared to the control side (d and e), whereas the expression level of c-Hes5 was slightly decreased in Sox3 transfected cells (f). Embryos were analyzed 44 h after electroporation.
