Synaptic vesicle fusion and synaptotagmin: 2B or not 2B?
Vincent O'Connor
& Anthony G. Lee
The authors are in the Divisions of Cell Sciences and Biochemistry and Molecular Biology, School of Biological Sciences, University of Southampton, Southampton, SO16 7PX, UK. voconno@soton.ac.uk; agl@soton.ac.uk
Whether synaptotagmin is the calcium sensor in transmitter release has been controversial. Two studies now highlight how calcium binding to synaptotagmin might support this function.
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