Quick-change artist: from excitatory to inhibitory synapse in minutes
Story C. Landis
The author is at the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bldg. 36, Rm. 5A05, 36 Convent Dr., Bethesda, Maryland 20892-4150, USA. landiss@ninds.nih.gov
Cultured sympathetic neurons contain an excitatory transmitter, norepinephrine, and one that is inhibitory, acetylcholine. A new paper shows that BDNF increases the ratio of acetylcholine to norepinephrine release, reversing the effect of neural stimulation from excitation to inhibition.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated
