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Nature Neuroscience  5, 1251 - 1252 (2002)
doi:10.1038/nn1202-1251

Stem cells that know their place

Seth Blackshaw & Constance L. Cepko

The authors are in the Department of Genetics and the Howard Hughes Medical Institute, Harvard Medical School, 200 Longwood Ave., Boston, Massachusetts 02115, USA. cepko@genetics.med.harvard.edu

Human neural stem cells could be used to treat many diseases, but a major problem with this approach is that these cells give rise to few neurons in the brain. Now a new priming method increases production of neurons after implantation, including the elusive cholinergic neurons.

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RESEARCH
Region-specific generation of cholinergic neurons from fetal human neural stem cells grafted in adult rat
Nature Neuroscience Article (01 Dec 2002)

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Open Innovation Challenges

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See also: Article by Wu et al.
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Nature Neuroscience
ISSN: 1097-6256
EISSN: 1546-1726
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