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Volume 5 Issue 11, November 2002

Differentiating neurons extend multiple processes, yet only one is destined to become the axon. Using the powerful genetic tools available in C. elegans, Yishi Jin and colleagues found that syd-1 is important for localizing presynaptic components to the developing axonal compartment, an important step in distinguishing the axon from dendrites. See pages 1107 and 1137.

Editorial

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Letters to Editor

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News & Views

  • Shape-selective neurons in inferotemporal cortex could carry information about either component parts or whole objects. A new paper now reports that whole-object shape selectivity is increased for stimuli that monkeys have learned to recognize in a discrimination task.

    • Charles E. Connor
    News & Views
  • A molecule that may be important for sorting presynaptic components into the developing axon is now revealed by a study using the genetic tools available in C. elegans.

    • Jessica L. Whited
    • Paul A. Garrity
    News & Views
  • A new study provides the strongest evidence yet that a smaller hippocampus may be a predisposing factor toward, rather than a consequence of, post-traumatic stress disorder.

    • Robert M. Sapolsky
    News & Views
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Book Review

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Brief Communication

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Commentary

  • There is growing public awareness of the ethical issues raised by progress in many areas of neuroscience. This commentary reviews the issues, which are triaged in terms of their novelty and their imminence, with an exploration of the relevant ethical principles in each case.

    • Martha J. Farah
    Commentary
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Review Article

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Article

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Focus

  • This supplement grew out of our curiosity about how neuroscience has contributed to improving the quality of people's lives. Fifteen review articles discuss recent progress toward a variety of practical applications of basic neuroscience, including memory enhancement, brain-computer interfaces, biotechnology of taste and smell, virtual reality, face recognition software, spinal cord injury and many others. In addition, five commentaries suggest ways to optimize the transfer of basic research to uses outside the laboratory. This special issue was supported by the National Institute of Neurological Disorders and Stroke and the National Institute on Drug Abuse.

    Focus
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