Protofibrils, the unifying toxic molecule of neurodegenerative disorders?
Christian Haass
& Harald Steiner
The authors are in the Laboratory for Alzheimer's Disease Research, Department of Biochemistry, Adolf-Butenandt-Institute; Schillerst Ludwig-Maximilians-University-Munich44, 80336 Munich, Germany. chaass@pbm.med.uni-muenchen.de; hsteiner@pbm.med.uni-muenchen.de
A newly identified Alzheimer's mutation leads to the suggestion that protofibril intermediates in amyloid plaque formation may be a crucial factor in pathogenicity.
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