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Molecular stepping stones in memory consolidation

Nature Neuroscience volume 4, pages 769–771 (2001)Cite this article

After a learning experience, memories are vulnerable to disruption during a consolidation period. Antisense against the transcription factor C/EBPβ in the hippocampus is now reported to disrupt the initial consolidation of memories, but not their 'reconsolidation' after later recall.

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Figure 1: The CREB-C/EBP pathway regulating gene expression thought to be required for memory formation.

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Authors and Affiliations

  1. Department of Neurobiology and Behavior and the Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, 92697, California, USA

    Thomas J. Carew & Michael A. Sutton

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  1. Thomas J. Carew
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  2. Michael A. Sutton
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Carew, T., Sutton, M. Molecular stepping stones in memory consolidation. Nat Neurosci 4, 769–771 (2001). https://doi.org/10.1038/90458

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