Brain calculus: neural integration and persistent activity
David A. McCormick
The author is in the Section of Neurobiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut, 06510, USA. david.mccormick@yale.edu
Tank and colleagues make in vivo intracellular recordings from neurons in a 'neural integrator' of the goldfish involved in maintaining eye position. In this circuit, 'working' memory may be the result of persistent changes in the state of the local network.