Illuminating the location of brain glutamate receptors
George J. Augustine
The author is in the Department of Neurobiology, Duke University Medical Center, Box 3209, Durham, North Carolina 27710, USA. georgea@neuro.duke.edu
Local glutamate application is often achieved by removing a chemical 'cage' with ultraviolet light. Matsuzaki et al. report a new method for uncaging glutamate with infrared light, and show that the shape of individual dendritic spines correlates with AMPA receptor responses.
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