Nature Neuroscience
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June 2000 - Vol 3 No 6
Nature Neuroscience 3 (2000)
 
Cover image detail
McKernan et al. use transgenic mice with a point mutation in a GABAA receptor subunit to dissociate the anxiolytic actions of diazepam (shown here) and related drugs from their sedative effects. They also describe a new ligand for the benzodiazepine binding site, which in normal mice produces anxiolytic effects without sedation. Photo courtesy of Sharon Freeman. See pages 529.529 and 587.
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