Preassembly and transport of nerve terminals: a new concept of axonal
transport
Jack Roos
& Regis B. Kelly
The authors are in the Department of Biophysics and
Biochemistry, University of California, San Francisco,
California 94143-0448, USA. rkelly@biochem.ucsf.edu
A morphological study suggests a new view of synapse formation by
demonstrating that presynaptic elements are assembled into 'prototerminals'
before being transported down axons by fast, saltatory movement. These structures
stop moving when the axon contacts a dendrite.