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Nature Neuroscience  3, 415 - 417 (2000)
doi:10.1038/74773

Preassembly and transport of nerve terminals: a new concept of axonal transport

Jack Roos & Regis B. Kelly

The authors are in the Department of Biophysics and Biochemistry, University of California, San Francisco, California 94143-0448, USA. rkelly@biochem.ucsf.edu

A morphological study suggests a new view of synapse formation by demonstrating that presynaptic elements are assembled into 'prototerminals' before being transported down axons by fast, saltatory movement. These structures stop moving when the axon contacts a dendrite.

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Open Innovation Challenges

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See also: Article by Ahmari et al.
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Nature Neuroscience
ISSN: 1097-6256
EISSN: 1546-1726
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