An orphan glutamate channel points the way to the gates
Johannes J. Krupp
& Gary L. Westbrook
The authors are at the Vollum Institute, Oregon Health
Sciences University, 3181 SW Sam Jackson Park Road,
Portland, Oregon 97201 USA
kruppj@ohsu.edu
How does the binding of agonist lead to a change in ion channel
gating? Kohda and colleagues take advantage of the lurcher mutation to provide
new insights into how binding of glutamate affects channel gating for AMPA,
kainate and NMDA receptors.
