Neurodegeneration in the polyglutamine diseases: Act 1, Scene 1
Robert Nussbaum
& Georg Auburger
The authors are at the National Human Genome Research
Institute, National Institutes of Health, 49 Convent Drive,
Bethesda, Maryland 20892, USA.
rlnuss@nhgri.nih.gov or auburger@nhgri.nih.gov
A mouse model of the neurodegenerative disease spinocerebellar ataxia type
1 reveals that changes in gene expression begin many weeks before the onset
of symptoms.
