 | Figure 2
Nature Neuroscience
3, 1232 - 1234 (2000)
doi:10.1038/81746
Closing in on a mammalian touch receptorMonica Driscoll
& Nektarios Tavernarakis | | | | Figure 2. Immunostaining of BNC1 around hair follicles in wild-type mice and comparison of mechanosensory responses.
(a) The anatomy of a hair follicle. (b) Confocal image of an oblique section through a hair follicle showing concentrated staining in lanceolate endings. h, hair follicle, g, sebaceous gland. (c) Comparison of RA mechanoreceptor responses from wild-type mice and BCN1-/- mutants. Wild-type RA mechanoreceptors elicit action potentials only in response to initial rapid displacement of the skin. RA neurons from the BNC1-/- mouse failed to increase action potential discharges in the lowest displacement stimulus range. (d) Comparison of stimulus−response curves for RA and SA mechanoreceptors in wild-type mice and BCN1-/- mutants. Reprinted by permission from Nature (ref. 3), copyright (2000) Macmillan Magazines Ltd.
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