 | Figure 1
Nature Neuroscience
3, 1232 - 1234 (2000)
doi:10.1038/81746
Closing in on a mammalian touch receptorMonica Driscoll
& Nektarios Tavernarakis | | | | Figure 1. A molecular model of a touch-transducing complex in C. elegans mechanosensory touch receptor neurons, based on genetic and molecular studies.
Protein contacts in a specialized extracellular matrix (called the mantle) and in the cytoskeleton are postulated to exert tension on the MEC-4/MEC-10 degenerin ion channel. The mechanical force of a touch to the cuticle pulls on the channel and physically gates it.
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