An ambiguous fast synapse: a new twist in the tale of two transmitters
Michael W. Salter1
& Yves De Koninck2
1
Michael Salter is at the Department of Physiology,
University of Toronto, Hospital for Sick Children, 555 University
Ave., Toronto, Ontario, M5G 1X8,
Canada. mike.salter@utoronto.ca
2
Yves De Koninck is at the Department of Pharmacology
& Therapeutics, McGill University, Montréal,
Québec, H3G 1Y6, Canada.
ydk@spinalcord.mcgill.ca
Jo and Schlichter describe GABA and ATP corelease from the same presynaptic
cell, which suggests that a dorsal horn synapse could be excitatory or inhibitory
depending on its postsynaptic receptors or the amount of transmitter released.
