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Weighing the evidence: how the brain makes a decision

Abstract

Kim and Shadlen investigate how neurons of the prefrontal cortex interpret slowly accumulating signals from visual cortex to make a perceptual decision.

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Figure 1: To earn a reward, monkeys had to decide the net direction of motion of a stimulus composed of variable fractions of coherently and randomly moving dots.

References

  1. Schall, J. D. & Bichot, N. P. Curr. Opin. Neurobiol. 8, 211–217 (1998).

    Article  CAS  Google Scholar 

  2. Leon, M. I. & Shadlen, M. N. Neuron 21, 669–672 (1998).

    Article  CAS  Google Scholar 

  3. Schall, J. D. & Thompson, K. G. Annu. Rev. Neurosci. 22, 241–259 (1999).

    Article  CAS  Google Scholar 

  4. Parker, A. J. & Newsome, W. T. Annu. Rev. Neurosci. 21, 227–277 (1998).

    Article  CAS  Google Scholar 

  5. Britten, K. H., Newsome, W. T., Shadlen, M. N., Celebrini, S. & Movshon, J. A. Vis. Neurosci. 13 , 87–100 (1996).

    Article  CAS  Google Scholar 

  6. Shadlen, M. N., Britten, K. H., Newsome, W. T. & Movshon, J. A. J. Neurosci. 16, 1486–1510 (1996).

    Article  CAS  Google Scholar 

  7. Schall, J. D. in Extrastriate Cortex of Primates, Vol. 12 Cerebral Cortex (eds. Rockland, K, Peters, A. & Kaas, J.) 527–638 (Plenum, New York, 1997).

    Book  Google Scholar 

  8. Shadlen, M. N. & Newsome, W. T. Proc. Natl. Acad. Sci. USA 93, 628–633 (1996).

    Article  CAS  Google Scholar 

  9. Editorial. Nat. Neurosci. 1, 535 (1998).

  10. Logothetis, N. K. & Schall J. D. Science 245, 761–763 (1989).

    Article  CAS  Google Scholar 

  11. Dennett, D. C. Elbow Room: The Varieties of Free Will Worth Wanting (MIT Press, Cambridge, MA, 1984).

    Google Scholar 

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Schall, J. Weighing the evidence: how the brain makes a decision. Nat Neurosci 2, 108–109 (1999). https://doi.org/10.1038/5663

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