Silent synapses: I can't hear you! Could you please speak aloud?
Antonio Malgaroli
Antonio Malgaroli is at the Unit of Neurobiology of Learning, Scientific Institute San Raffaele,Via Olgettina 58, Milano 20132, Italy. malgaroli.antonio@mail.hsr.it
Cyclic AMP application mimics the late phase of long-term potentiation
in hippocampal CA3−CA1 cultures. Now imaging with FM1-43 shows that
this activity-dependent change in synaptic strength involves the recruitment
of pre-existing, presynaptically silent synapses.