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Decoding and deorphanizing an olfactory map

As conversion of odor signals to a two-dimensional map of activated glomeruli in the olfactory bulb is the key to odor recognition, decoding and deorphanizing of odorant receptors in the olfactory map is of great interest. Two genome-wide techniques now offer the ability to pair any odorant with its receptors.

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Figure 1: Two new strategies for deorphanizing ORs in the activated glomeruli of the olfactory bulb (OB) in the awake animal.

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Correspondence to Hitoshi Sakano.

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Nishizumi, H., Sakano, H. Decoding and deorphanizing an olfactory map. Nat Neurosci 18, 1432–1433 (2015). https://doi.org/10.1038/nn.4121

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