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Tuning synaptic activity with light-controlled GPCRs

A study reporting spatiotemporal stimulation and inhibition of synaptic activity is made possible by the development of synaptically targeted, light-controlled G protein–coupled receptors.

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Figure 1: Light modulation of synaptic activity using light-controlled mGluRs.

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Correspondence to Jean-Philippe Pin.

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Pin, JP. Tuning synaptic activity with light-controlled GPCRs. Nat Neurosci 16, 377–379 (2013). https://doi.org/10.1038/nn.3363

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