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Tune in to KCNQ

A study finds that the voltage-gated K+ channel KCNQ4 is expressed in a subset of rapidly adapting, low-threshold mechanoreceptors, where it shapes the response profile to dynamic tactile stimuli.

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Figure 1: KCNQ4 shapes Aβ rapidly adapting LTMR tuning to dynamic mechanical stimuli.

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Acknowledgements

This work was supported by the US National Institutes of Health (NS054902) and the Blaustein Pain Research Fund.

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Correspondence to Michael J Caterina.

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The authors declare no competing financial interests.

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Munns, C., Caterina, M. Tune in to KCNQ. Nat Neurosci 15, 8–10 (2012). https://doi.org/10.1038/nn.3012

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