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Nature Neuroscience 12, 1077 - 1079 (2009)
doi:10.1038/nn0909-1077
Be careful what you train for
Wolfram Tetzlaff1, Karim Fouad3 & Brian Kwon1,2
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Wolfram Tetzlaff and Brian Kwon are at the International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, Canada.
e-mail: tetzlaff@icord.org - Brian Kwon is also affiliated with the Department of Orthopedic Surgery at the University of British Columbia.
- Karim Fouad is at the Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada.
Abstract
No effective therapeutic interventions exist for severe spinal cord injury. A report in this issue shows that rats can recover substantial 'hand' function after complete lesion of the cervical dorsal corticospinal tract, if treated with a combination of specific reaching rehabilitation exercises and chondroitinase injections to enhance axonal sprouting.
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