Brief Communication abstract


Nature Neuroscience 12, 967 - 969 (2009)
Published online: 28 June 2009 | doi:10.1038/nn.2352

Resolving single cone inputs to visual receptive fields

Lawrence C Sincich1, Yuhua Zhang2,3, Pavan Tiruveedhula2, Jonathan C Horton1 & Austin Roorda2

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With the current techniques available for mapping receptive fields, it is impossible to resolve the contribution of single cone photoreceptors to the response of central visual neurons. Using adaptive optics to correct for ocular aberrations, we delivered micron-scale spots of light to the receptive field centers of neurons in the macaque lateral geniculate nucleus. Parvocellular LGN neurons mapped in this manner responded with high reliability to stimulation of single cones.

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  1. Beckman Vision Center, University of California, San Francisco, San Francisco, California, USA.
  2. School of Optometry, University of California, Berkeley, Berkeley, California, USA.
  3. Department of Ophthalmology, University of Alabama, Birmingham, Alabama, USA.

Correspondence to: Lawrence C Sincich1 e-mail: sincichl@vision.ucsf.edu.



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